Job title: Senior Principal Scientist
Cris Kamperschroer was trained as an immunologist. His academic work focused primarily on different aspects of T cell biology, most often in the context of viral infections. Cris has been at Pfizer in Groton, Connecticut for the past 11 years. In his current role, he handles immunology-related safety issues, primarily in the area of oncology, and he serves as the lead for safety assessment on multiple projects in immuno-oncology.
Panel Discussion: Focusing on Dosing Regimens and the Therapeutic Window in order to Develop Easily Administered Drugs 2:15 pm
• Exploring the potential ability of drugs with short serum half-lives allowing precise control of drug levels within the patient to enhance their potential safety • Determining the exposure levels needed for cell engagers to be effective • Understanding the importance of dose selection and escalation • What preclinical information is actually useful? • Do…Read more
day: Day Two
Reducing Key Toxicities with T Cell Engaging Bispecifics 8:30 am
• What are the key toxicities that are common with T cell engagers? • Exploring strategies Pfizer has used to detect and minimize potential toxicities, with a focus on solid tumor indications • Examining how to reduce CRS with different approaches, including pharmacological blockade of cytokinesRead more
day: Day Two