Kristel Kemper

Kristel Kemper

Company: Genmab

Job title: Principal Scientist


Mechanistic & Pharmacodynamic Studies of Duobody-CD3x5T4 In Preclinical In Vitro & In Vivo Models 2:40 pm

Discuss DuoBody®-CD3x5T4, an Fc-silenced CD3 bsAb that crosslinks CD3 on T cells with 5T4 on tumor cells Hear how T-cell mediated cytotoxicity was induced by DuoBody-CD3x5T4 in 5T4+ tumor cells, associated with T-cell activation, proliferation and cytokine production in vitro Learn how DuoBody-CD3x5T4 has shown preclinical anti-tumor activity in multiple solid cancer CDX/PDX models in…Read more

day: Day One

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