Advancing T‑Cell Engagers: Addressing Key Efficacy & Safety Challenges
- Outlining genO-BRGSF-HIS mice: a CD34+-reconstituted model with functional human lymphoid and myeloid compartments, without side effects
- Highlighting the key contribution of myeloid cells in the assessment of cytokine release induced by TCE
- Evidencing the recruitment of human immune cells to tumor microenvironment, as well as their activation status