XmAb819: Avidity-Driven Selectivity in T-Cell Engagers Using Xencor’s 2+1 Platform

  • Discussing different T-Cell Engager configurations such as 1+1 and 2+1 as strategies for selectivity
  • Examining how dual-antigen engagement enables simultaneously binding that increases functional avidity and exploring factors that impact avidity
  • Presentation of pre-clinical and clinical data in RCC