Bin Xie
Research & Executive Director, Immuno-Oncology LIDE
Seminars
Wednesday 24th June 2026
Speech: A Translational Approach to Evaluate T Cell Engagers & Bispecific Antibodies in Humanized Animal Models
1:00 pm
- Development of Co-inoculated tumor/PBMC animal models to assess the efficacy and immune-mediated mechanisms of T cell engagers and bispecific antibodies
- Application of IO-FIVE, a humanized MiniPDX platform to evaluate T cell engagers in fresh patient-derived samples
- Establishment of clinically relevant animal models to support candidate selection and optimization
