Targeted PD-1 Agonists as Localized Immune Suppressants Against Autoimmune Diseases
Time: 3:15 pm
day: Day 1
Details:
- Developing immunosuppressive bispecifics consisting of high affinity targeting domain fused to a PD-1 agonist to treat autoimmune diseases
- Inhibiting T cell activity by activating PD-1 pathway only when molecules are bound to
- target cells
- Delivering tissue-restricted T cell inhibition while avoiding systemic immunosuppression
