9.00 Expanding Strategic Insights from Early Clinical Trial Development to Improve Successful Development of Cell Engagers
Time: 9:00 am
day: Workshop B
Details:
It remains vital to understand early clinical trial design to ensure progression, safety, and efficacy of this highly potent modality. Implement thoughtful patient selection, guided by logical biomarker choices to minimize risk and improve patient outcomes. Explore early trial design, including dosing and close patient monitoring to establish efficacy profiles. Debate different clinical trial design approaches for determining dosage and maintaining patient comfort.
- Establishing optimal dosing regimens to evaluate potential side effects and inform patient selection based on biomarkers
- Navigate narrow therapeutic windows alongside patient variation and discuss factors such as tumor burden, immune function, and overall patient health
- Refine early clinical development to understand and predict potential adverse effects including CRS
