Mitigate Toxicity by Engineering & Assembling Novel Formats to Mitigate Toxicity
Time: 2:30 pm
day: Conference Day 1
Details:
- Optimizing protein structure of BITEs to achieve increased selectivity of binding to tumor cells to minimize interactions with healthy tissue
- Navigating reducing affinity to reduce risk of CRS and toxicity, compared to decreased potency and risk reducing efficacy
- Explore the promise of tri- and multi-specific cell engagers for dual targeting
